For more information on multiple myeloma survival rates and life expectancy go to the web site www.myelomasurvival.com, or you can follow me on my twitter account at: https://twitter.com/grpetersen1
Every time we get a new drug in the multiple myeloma treatment arsenal, the life expectancy and survival rates make a jump upward. We currently have alkylating agents(melphalan), immunomodulatory drugs(Thalamid), proteasome inhibitors(Velcade), and steroids(dexamethasone). Now there is a new class of drugs called Monoclonal Antibodies(Daratumumab), which uses the body's own immune system to attack the myeloma. It is this new class of drugs which Dr. Asher Chanan-Khan of Mayo Clinic discussed at the November 21st Cure Panel Broadcast. You can listen to this broadcast about this exciting new class of drugs if you CLICK HERE. Nick Van Dyk provided a summary of this presentation on his blog, and you can see it if you CLICK HERE. I was at an IMF meeting at Mayo Clinic where Dr. Chanan-Kahn was a presenter. He explained the biology of multiple myeloma along with his treatment philosophy, with his only prop being a RED SOLO CUP. All of the people that I talked with after the meeting were impressed with his ability to bring such a complex disease and it treatments to a level where we all understood and were quite impressed. Dr. Chanan-Kahn explained that he believes in the philosophy that "Less is Best" when it comes to treatment, and he is not a proponent of stem cell transplant. I think you will find this broadcast to be one that you will look back on as a great educational experience.
For more information on multiple myeloma survival rates and life expectancy go to the web site www.myelomasurvival.com, or you can follow me on my twitter account at: https://twitter.com/grpetersen1
7 Comments
Mark
11/19/2013 06:31:11 am
Hi Gary,
Reply
11/20/2013 12:44:20 am
Mark, thanks for your allo research. We know you will be up to date on the most recent allo information. It does seem that Moffitt has unlocked the key to success from the mini allo transplant. I also think that your statement "high risk younger patients might want to consider a trip to Moffitt for an opinion" has merit. I know that Dr. Hari in Milwaukee has recommended the auto/mini allo to a very young high risk patient.
Reply
Ed
4/28/2014 12:59:27 am
I know it has been awhile since Dr. Khan's monoclonal antibody cure talk discussion participation but I recently listened to the program and in the last few minutes thereof, in response to the last listener question posed regarding monoclonal antibody therapy relative to non-secreters, Dr. Khan mentioned a trial and/or antibody that seemed to have particular effectiveness vs "light chains". Do you have any further info and/or can direct me to where I may be able to acquire more info regarding this particular antibody? I'm presently being treated by Dr. Barlogie at UAMS for Lambda Light Chain MM on TT4 "like" protocol. Dx'ed in 3/2011.
Reply
4/28/2014 09:43:57 pm
Ed, I listened to the part of the broadcast you mention, and Dr. Chanan-Khan mentioned a new antibody but did not name it. I will forward your email to him and hopefully he will provide you the name. Gary
Reply
Ed
4/29/2014 12:45:37 am
Gary, thanks for your quick response. 4/29/2014 09:47:46 pm
Dr. Chanan Kahn provided the following reply: "That is a drug from Genentech that is being investigated in phase 1study and too early to make and strong conclusions However, preliminary work so far look promising" I did a little followup research and found the attached clinical trial of a monoclonal antibody called SGN-40 and a link is:http://www.cancer.gov/clinicaltrials/search/view?cdrid=362069&version=HealthProfessional&protocolsearchid=12549660
Reply
9/22/2014 12:53:32 am
Comments are closed, please email me at editor@myelomasurvival.com
Reply
Your comment will be posted after it is approved.
Leave a Reply. |
AuthorGary R. Petersen Categories |